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WELCOME TO THE

Endocannabinoid

SYSTEM

What's an Endocannabinoid?

It is the system at work inside of all animals
The endogenous cannabinoid system, named after the plant that led to its discovery, is perhaps the most important physiologic system involved in establishing and maintaining human health.

Why you should eat cannabis

Eating cannabis enables the beneficial cannabinoids found in Marijuana to become available to your Endocannabinoid System. What is the Endocannabinoid System?

It all started with a scientific breakthrough in 1964, when a scientist from Israel named Raphael Mechoulam was able to identify and isolate THC for the first time – just prior to which they were able to identify CBD as well.

Isolating these cannabinoids was the first stepping stone in discovering the endocannabinoid system – a biological system that can be found in just about any living thing with vertebrae.

In 1988, the first cannabinoid receptor was found in the brain of a rat. Initially found by Allyn Howlett and William Devane these cannabinoid receptors turned out to be plentiful in the brain – more so than any other neurotransmitter receptor.

It wasn’t until two years later in 1990 before the next big breakthrough; when Lisa Matsuda announced at the National Academy of Science’s Institute of Medicine that she and her colleagues at the National Institute of Mental Health had managed to pinpoint the DNA sequence that defines a THC-sensitive receptor in a rat’s brain.

Soon after, in 1993, a second cannabinoid receptor was found – as a part of the immune and nervous systems. Dubbed CB2 (the CB receptors in the brain officially dubbed CB1 receptors) receptors they are found to be plentiful throughout the gut, spleen, liver, heart kidneys, bones, blood vessels, lymph cells and even the reproductive organs.

However that curious, pesky question remained unanswered – why do we have cannabinoid receptors in the first place?

The endocannabinoid system is possibly the single-most important system within our entire bodies – responsible for maintaining homeostasis. Basically, if our endocannabinoid system is out-of-whack, your whole body could be at risk as it is responsible for many of our normal day to day functions.

The possibilities that come with understanding the endocannabinoid system are practically endless. This one system helps to regulate almost every aspect of our well-being – meaning if we can learn to manipulate these receptors (with use of cannabinoids from cannabis) we could possibly have the answer to not only curing diseases, but preventing them all together.

A little history

All of this sort of makes you wonder why Cannabis was delared a Schedule 1 drug in the US and under pressure from the US, other countries did the same. This all started around 1903 roughly the same time that Aspirin started to gain interest. By 1915, Aspirin was being sold as over-the-counter tablets.

Cannabis prohibitions began in the 1920s and by the 30's cannabis was regulated as a drug in every state. Cannabis was officially outlawed for any use (medical included) with the passage of the Controlled Substances Act (CSA) of 1970.

Multiple efforts to reschedule cannabis under the CSA have failed, and the U.S. Supreme Court has ruled in United States v. Oakland Cannabis Buyers' Cooperative and Gonzales v. Raich that the federal government has a right to regulate and criminalize cannabis, even for medical purposes.

All information provided is sourced from around the WWW and while we try to verify everything it is important to understand that this information may be incorrect or incomplete.

We do not promote illegal use of cannabis. Please adhear to the laws in your area.

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